Diagnosing Equine Pituitary Pars Intermedia Dysfunction in Ambulatory Practice
نویسنده
چکیده
Diagnosis of pituitary pars intermedia dysfunction can be achieved in the field using the dexamethasone suppression test or plasma adrenocorticotropic hormone (ACTH). Equine ACTH is considerably more stable than previously suggested, which makes it useful for field-collected samples. Fasting insulin and circadian cortisol concentration are not discriminating tests. Additionally, season may affect interpretation of diagnostic test results. Author’s address: Department of Physiological Sciences, 264 McElroy, Oklahoma State University, Stillwater, OK 74078; e-mail: [email protected]. © 2008 AAEP.
منابع مشابه
Equine Cushing’s Disease or Equine Pituitary Pars Intermedia Dysfunction (PPID) Keeping up with Evolution
In 1932, Pallaske reported a condition in geriatric horses that resulted in a long, curly hair coat and an enlarged pituitary gland [1]. This disease, known as Equine Cushing’s Disease, or re-named as equine pituitary pars intermedia dysfunction (PPID) is now commonly recognized in equine practice, partly because of the increasing geriatric equine population. PPID is a primary problem of the pi...
متن کاملThe pharmacologic basis for the treatment of endocrinopathic laminitis.
Although the treatment and management of laminitis in the horse requires a holistic and often multidisciplinary approach from the veterinarian, farrier, and nutritionist, this review focuses on pharmacologic interventions that might have prophylactic benefit, specifically in the horse with laminitis as a result of pituitary pars intermedia dysfunction and equine metabolic syndrome.
متن کاملThe Role of Dopaminergic Neurodegeneration in Equine Pituitary Pars Intermedia Dysfunction (Equine Cushing's Disease) (21-Nov-2003)
Equine pituitary pars intermedia dysfunction (PPID) is a well-recognized disease in aged horses and ponies, yet the etiology and pathophysiology of this condition remains poorly understood. Immunohistochemistry of formalin-fixed pituitary tissue was used to demonstrate dopaminergic neurodegeneration and oxidative stress in the pars intermedia in horses with PPID. The role of oxidative stress in...
متن کاملEndocrinopathic Laminitis, Obesity-Associated Laminitis, and Pasture-Associated Laminitis
In a recent online survey, we asked equine practitioners to list the three most common causes of laminitis in horses seen within their practice. We expected veterinarians to list colitis, colic, and retained placenta as the primary causes of laminitis, but many respondents listed obesity, insulin resistance (IR), equine metabolic syndrome (EMS), pituitary pars intermedia dysfunction (PPID), and...
متن کاملPituitary pars intermedia dysfunction: equine Cushing's disease.
PPID in older equids has become a major health concern of horse owners. In response, equine practitioners have made greater efforts at understanding, diagnosing, and treating this disorder. Although PPID is recognized to be a different form of pituitary-dependent hyperadrenocorticism than is seen in canine or human patients, relatively little is known about the pathophysiology and natural progr...
متن کامل